If the spec requires Loctite then you can't use anti-sieze grease needed for use with any titanium fastener. So this connection may not be suitable for a titanium replacement.
Titanium and Stainless Steel Fasteners
One of the design considerations for a motorcycle is corrosion resistance. So when you disassemble it, make changes or replace components, and reassemble it, you need to be aware of a few things.
The manufacturer uses a number of different metal alloys, plastics, and coatings - each selected for its cost, weight, strength, appearance, and corrosion resistance among other things. What also needed to be considered, is that when any two different metals touch each other, electricity flows between them (which is how a battery works), and the surface of the metal lower on the list (below) corrodes.
For example, when aluminum or magnesium are in contact with carbon or stainless steel, this galvanic action will corrode the aluminum or magnesium. So the approach is to use steel fasteners to fasten steel parts together, whenever possible.
One problem is that aluminum fasteners aren’t very strong, so aluminum parts are held with steel fasteners, but in special ways to reduce corrosion. Carbon steel bolts threaded directly into aluminum is generally avoided, for example.
Here’s a list of some commonly used metals. The farther apart (top to bottom) on the list the two materials are, the more corrosion that will occur to the material lower on the list when they are held in contact.
Stainless steel, type 316
Zinc (commonly used as a sacrificial anode in marine environments)
One way to control this galvanic corrosion is to use metals closer to each other in the above list, or by electrically-isolating metals from each other. Cadmium plating of steel fasteners for example, is used to reduce the metal dissimilarities with aluminum and magnesium. Paint and coatings are used to prevent metals from touching.
Keeping the two dissimilar metals dry will also slow the corrosion process but just the moisture in the air on a humid day is enough to cause a problem.
If a fastener won’t get disassembled for long periods of time, it’s a candidate for using an anti-seize compound during assembly. There are three formulations widely available based on copper, aluminum or nickel.
The way anti-seize compounds work is by placing a third dissimilar metal between the two base metals. So the corrosion of a thread in a magnesium part caused by a titanium bolt is reduced by an intermediate copper-rich or nickel-rich thread coating grease. The aluminum anti-sieze compound is for use between (say) stainless steel and magnesium.
If the same materials are being fastened together, then they are assembled dry to the manufacturer’s torque values - unless otherwise specified. In critical fasteners such as the axle nut that holds the rear wheel on superbikes, the spec calls for lubricating the threads prior to assembly. The torque spec assumes a lubricated thread. Read your manual.
In general, a thread treated with either an anti-seize or regular grease requires a lower torque value (than a higher-friction dry thread) to create the same tension in the fastener. So, if you make a modification that changes a component material, such that anti-seize is now needed, you’ll need to torque the fastener to an approximately 10% lower value to avoid over-tensioning the fastener (according to Machinery's Handbook, 25th ed.). A new torque wrench is usually accurate to ± 3%.
If a bolt is torqued to the specified value there’s no need for thread locking adhesives. When the manufacturer is designing a critical connection that will be subjected to vibration, a lock washer is incorporated to prevent loosening.
So to sum-up, if you use titanium hardware to replace the cadmium-plated steel hardware, you can develop worse corrosion problems. The cadmium is sacrificial in the sense that it corrodes preferentially, thereby protecting aluminum and magnesium components assembled by/to it.
It depends on how the titanium (in fact, any material) fastener is used. The above picture shows the galvanic corrosion of an aluminum plate (after just six months) caused by using a stainless steel screw. The stainless itself doesn’t corrode, it causes the aluminum to corrode. The corrosion using a titanium fastener will be worse than for stainless.
In the above situation if you used a cadmium-plated steel screw (like Ducati stock hardware) the cadmium plating would corrode first, and in doing so, protect the aluminum part instead of the other way around.
In fact, that’s what you’re seeing when you’re looking to replace that scruffy-looking hardware ... the inexpensive fastener’s plating protecting the expensive aluminum and magnesium parts.
So, what I’m warning here is that if you replace your corroded fasteners with a corrosion-resistant (but more-dissimilar) material such as titanium or stainless steel, you can shift the corrosion to the aluminum or magnesium if the two dissimilar metals are touching. Anti-sieze materials will help by inserting a third material that itself will corrode but slow down the galvanic action.